scExplorer — Imputation

Step 3 · optional expression recovery

Imputation

Recover candidate dropout values without replacing the normalized analysis. Every run keeps a no-imputation baseline and processes all genes.

AnalysisNot loaded

Cells—

Genes—

InputAll genes

Skip to DEA

Checking analysis readiness

Counts, UMAP and grouping must be available.

Method

Choose the recovery model

Normalized baseline preserved

SP SPARESelective zero editing with intervention masks and biological audit. RecommendedEstimating… AL ALRAZero-preserving low-rank recovery with automatic rank selection. ComparatorEstimating… MG MAGICGraph diffusion for exploratory smoothing. Review false-signal audits carefully. ExploratoryEstimating…

Group cells Used for auditing and by SPARE's partition-aware model.

Random seed Recorded for reproducibility.

Advanced parametersDefaults follow each implementation.

SPARE selective · all genesWaiting for analysis dimensions.

Saved runs

History and comparison

	Run	Method	State	Intervention	Runtime	Storage	Actions
No imputation runs yet.

Imputation

Choose the recovery model

History and comparison

Imputation results

Imputation guide

Scientific safeguards